Clinical Studies
Anti-inflammation and joint mobility
  1. Evaluation of anti-inflammatory property of curcumin (diferuloyl methane) in patients with postoperative inflammation.
  1. Curcumin, an antioxidant and anti-inflammatory agent, induces heme oxygenase-1 and protects endothelial cells against oxidative stress
  1. Anti-inflammatory properties of curcumin, a major constituent
  1. Safety and anti-inflammatory activity of curcumin: a component of tumeric (Curcuma longa)
  1. Antioxidant and anti-inflammatory properties of curcumin
Anti-oxidant protection of cells from free radical damage
  1. Chemopreventive effect of curcumin, a naturally occurring anti-inflammatory agent, during the promotion/progression stages of colon cancer
  1. Role of phenolic OH and methylene hydrogen on the free radical reactions and antioxidantactivity of curcumin
  1. Curcumin induces glutathione biosynthesis and inhibits NF-κB activation and interleukin-8 release in alveolar epithelial cells: mechanism of free radical scavenging …
  1. Free radical scavenging ability and antioxidant efficiency of curcumin and its substituted analogue
  1. Antioxidant and radical scavenging properties of curcumin
Brain function and memory
  1. Effect of curcumin on brain insulin receptors and memory functions in STZ (ICV) induced dementia model of rat
  1. Brain foods: the effects of nutrients on brain function
  1. Dietary curcumin counteracts the outcome of traumatic brain injury on oxidative stress, synaptic plasticity, and cognition
  1. Plants used in Chinese and Indian traditional medicine for improvement of memory and cognitive function
  1. Neuroprotective effects of curcumin
Liver function
  1. Medicinal foodstuffs. XXIX. Potent protective effects of sesquiterpenes and curcumin from Zedoariae Rhizoma on liver injury induced by D-galactosamine …
  1. … protective effects of quercetin and curcumin on paracetamol-induced histological changes, oxidative stress, impaired liver and kidney functions and haematotoxicity in …
  1. Curcumin prevents alcohol-induced liver disease in rats by inhibiting the expression of NF-κB-dependent genes
  1. Protection of liver cells from ethanol cytotoxicity by curcumin in liver slice culture in vitro
  1. Pharmacological actions of curcumin in liver diseases or damage
Removal of toxins from the body
  1. Curcumin Decreases Binding of Shiga-Like Toxin-1B on Human Intestinal Epithelial Cell Line HT29 Stimulated with TNF-. ALPHA. and IL-1. BETA.: Suppression of …
  1. Curcumin reduces the toxic effects of iron loading in rat liver epithelial cells
  1. Photocytotoxicity of curcumin
  1. Targeted inhibition of glucuronidation markedly improves drug efficacy in mice—A model
  1. Curcumin protects mitochondria from oxidative damage and attenuates apoptosis in cortical neurons
Digestion
  1. Curcumin therapy in inflammatory bowel disease: a pilot study
  1. Curcumin and inflammatory bowel disease: biological mechanisms and clinical implication.
  1. Gastroesophageal reflux disease (GERD): a review of conventional and alternative treatments.
  1. Effects of curcumin on reflux esophagitis in rats
Joint Balance
  1. Kizhakkedath R. Clinical evaluation of a formulation containing Curcuma longa and Boswellia serrata extracts in the management of knee osteoarthritis. Mol Med Rep. 2013; 8:1542-8.
  1. Clutterbuck AL, Allaway D, Harris P, Mobasheri A. Curcumin reduces prostaglandin E2, matrix metalloproteinase-3 and proteoglycan release in the secretome of interleukin 1β-treated articular cartilage. 2013; 2:147.
  1. Mathy-Hartert M, Jacquemond-Collet I, Priem F, Sanchez C, Lambert C, Henrotin Y. Curcumin inhibits pro-inflammatory mediators and metalloproteinase-3 production by chondrocytes. Inflamm Res. 2009; 58:899-908.
  1. Kimmatkar N, Thawani V, Hingorani L, Khiyani R. Efficacy and tolerability of Boswellia serrata extract in treatment of osteoarthritis of knee–a randomized double blind placebo controlled trial. 2003; 10:3-7.
  1. Henrotin Y, Priem F, Mobasheri A. Curcumin: a new paradigm and therapeutic opportunity for the treatment of osteoarthritis: curcumin for osteoarthritis management. 2013; 2:56.
  1. Kapoor S. Curcumin and its emerging role in pain modulation and pain management. Korean J. Pain 2012; 25:202-203.
  1. Takahashi M, Suzuki K, Kim HK, Otsuka Y, Imaizumi A, Miyashita M, Sakamoto S. Effects of curcumin supplementation on exercise-induced oxidative stress in humans. Int J Sports Med. 2014; 35:469-75.
  1. Akazawa N, Choi Y, Miyaki A, Tanabe Y, Sugawara J, Ajisaka R, Maeda S. 2012. Curcumin ingestion and exercise training improve vascular endothelial function in postmenopausal women. 2012; 32:795-9.
  1. Davis JM, Murphy EA, Carmichael MD, Zielinski MR et al. Curcumin effects on inflammation and performance recovery following eccentric exercise-induced muscle damage. J. Physiol. 2007; 292: R2168-R2173.
  1. Kawanishi N, Kato K, Takahashi M, Mizokami T, Otsuka Y, Imaizumi A, et al. Curcumin attenuates oxidative stress following downhill running-induced muscle damage. Biochem Biophys Res Commun. 2013; 441:573-
Ultramicronized Turmeric Curcumin
  1. Jagetia GC, Aggarwal BB. “Spicing up” of the immune system by curcumin. J Clin Immunol. 2007; 27: 19-35.
  1. Menon V, Sudheer AR. Antioxidant and anti-inflammatory properties of curcumin. Adv Exp Med Biol. 2007; 595:105-125.
  1. Rao CV. Regulation of LOX and COX by curcumin. Adv Exp Med Biol. 2007; 595: 213-26.
  1. Gautam SC, Gao X, Dulchavsky S. Immunomodulation by curcumin. Adv Exp Med Biol. 2007; 595:321-41.
  1. Prasad S, Tyagi AK, Aggarwal BB. Recent developments in delivery, bioavailability, absorption and metabolism of curcumin: the golden pigment from golden spice. Cancer Res. Treat. 2014; 46:2-18.
  1. Agarwal KA, Tripathi CD, Aggarwal BB, Saluja S. Efficacy of turmeric (curcumin) in pain and post-operative fatigue after laparoscopic cholecystectomy: a double-blind, randomized placebo-controlled study. Surg. Endosc. 2011; 25:3805-10.
  1. Aggarwal BB. Targeting inflammation-induced obesity and metabolic diseases by curcumin and other nutraceuticals. Annu Rev Nutr. 2010; 30:173-99.
  1. Sikora E, Bielak-Zmijewska A, Mosieniak G, Piwocka K. The promise of slow down ageing may come from curcumin. Curr Pharm Des. 2010; 16:884-92.
  1. Aggarwal BB, Kumar A, and Bharti AC. Review. Anticancer potential of curcumin: preclinical and clinical studies. Anticancer Research. 2003; 23:363-398.
  1. Chuengsamarn S, Rattanamongkolgul S and Jirawatnotai S. Curcumin Extract for Prevention of Type 2 Diabetes. Diabetes Care 2012; 35: 2121-2127.
Gastrointestinal Balance
  1. Dulbecco P and Savarino V. Therapeutic potential of curcumin in digestive diseases. World J Gastroenterol 2013; 19: 9256-9270.
  1. Zhi L, Dong L, Kong D, Sun B, Sun Q, Grundy D, Zhang G, Rong W. Curcumin acts via transient receptor potential vanilloid-1 receptors to inhibit gut nociception and reverses visceral hyperalgesia. Neurogastroenterol Motil. 2013; 25:e429–e440.
  1. Rees, WD, Rhodes J, Wright JE, Stamford LF, Bennett A. (1979). Effect of deglycyrrhizinated liquorice on gastric mucosal damage by aspirin. J. Gastroenterol. 1979; 14: 605-607.
  1. Fukai T, Marumo A, Kaitou K, Kanda T, Terada S, Nomura T. Anti-Helicobacter pylori flavonoids from licorice extract. Life Sci. 2002; 71:1449-63.
  1. Borrelli F, Izzo AA. The plant kingdom as a source of anti-ulcer remedies. [Review]. Res. 2000; 14:581-591.
  1. Santo AM, Lopes T, Oleastro M, Gato IV et al. Curcumin inhibits gastric inflammation induced by helicobacter pylori infection in a mouse model. Nutrients 2015; 7:306-20.
  1. Rajasekaran SA. Therapeutic potential of curcumin in gastrointestinal diseases. World J Gastrointest. Pathophysiol. 2011; 15: 1-14.